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Real time monitoring of bioreactor mAb IgG3 cell culture process dynamics via Fourier transform infraredspectroscopy: Implications for enabling cell culture process analytical technology?

Huiquan Wu, Erik Read, Maury White, Brittany Chavez, Kurt Brorson, Cyrus Agarabi, Mansoor Khan

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 3,   Pages 386-406 doi: 10.1007/s11705-015-1533-3

Abstract: Understanding process dynamics of bioreactor cell culture process is essential to establish an appropriateInline spectroscopic techniques for real time monitoring of bioreactor cell culture process have theIn this work, real time inline FTIR Spectroscopy was applied to a lab scale bioreactor mAb IgG3 cellcell culture process.cell culture process via FTIR spectroscopy.

Keywords： PAT)     Fourier-transform infrared (FTIR) spectroscopy     partial least squares (PLS) regression     mouse IgG3     bioreactorcell culture process     real time process monitoring    

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Methanation and chemolitrophic nitrogen removal by an anaerobic membrane bioreactor coupled partial nitrification

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 6, doi: 10.1007/s11783-023-1668-2

Abstract:

● Efficient carbon methanation and nitrogen removal was achieved in AnMBR-PN/A system.

Keywords： Anaerobic membrane bioreactor     Partial nitrification/Anammox     Carbon separation     Chemolitrophic nitrogen    

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Preliminary study of groundwater denitrification using a composite membrane bioreactor

Lihui ZHANG, Guomin CAO, Yulei FEI, Hong DING, Mei SHENG, Yongdi LIU

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 4,   Pages 604-609 doi: 10.1007/s11783-011-0274-x

Abstract: A composite membrane bioreactor (CMBR) integrating the immobilized cell technique and the membrane separationthe composite membrane consisting of a microporous membrane facing the influent and an immobilized cellNitrate and ethanol molecules diffused from the respective compartments into the immobilized cell membraneThe microporous membrane was attached to one side of the immobilized cell membrane for retention of the

Keywords： groundwater     nitrate     denitrification     composite membrane bioreactor (CMBR)     immobilized cell membrane    

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Enhanced atrazine removal using membrane bioreactor bioaugmented with genetically engineered microorganism

LIU Chun, HUANG Xia

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 4,   Pages 452-460 doi: 10.1007/s11783-008-0050-8

Abstract: Bioaugmentation with genetically engineered microorganisms (GEMs) in a membrane bioreactor (MBR) forIn contrast, in a conventionally activated sludge bioreactor (CAS), sludge bulking occurred possibly
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Recent advances in membrane bioreactor technology for wastewater treatment in China

Xia HUANG, Kang XIAO, Yuexiao SHEN

Frontiers of Environmental Science & Engineering 2010, Volume 4, Issue 3,   Pages 245-271 doi: 10.1007/s11783-010-0240-z

Abstract: Since the introduction of the membrane bioreactor (MBR) in China in the early 1990s, remarkable progress

Keywords： membrane bioreactor (MBR)     municipal wastewater treatment     industrial wastewater treatment     membrane fouling    

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Bisphenol A removal from synthetic municipal wastewater by a bioreactor coupled with either a forward

Hongtao ZHU, Wenna LI

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 2,   Pages 294-300 doi: 10.1007/s11783-013-0486-3

Abstract: Forward osmotic membrane bioreactor is an emerging technology that combines the advantages of forwardosmosis and conventional membrane bioreactor.In this paper, bisphenol A removal by using a forward osmotic membrane bioreactor and a conventionalmembrane bioreactor that shared one biologic reactor was studied.bioreactor was as high as 93.9% and 98%, respectively.

Keywords： forward osmosis     membrane bioreactor     bisphenol A     microfiltration    

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wastewater treatment plants retrofitted from the conventional activated sludge process to the membrane bioreactor

Frontiers of Environmental Science & Engineering doi: 10.1007/s11783-021-1483-6

Abstract: (WWTPs) are being retrofitted from the conventional activated sludge (CAS) process to the membrane bioreactor

Keywords： Membrane bioreactor (MBR)     Conventional activated sludge (CAS)     Cost-benefit analysis     Data envelopment    

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Performance of bioferric-submerged membrane bioreactor for dyeing wastewater treatment

ZOU Haiyan, XI Danli

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 3,   Pages 374-380 doi: 10.1007/s11783-007-0064-7

Abstract: In view of this, Fe(OH) was added to a submerged membrane bioreactor (SMBR) to enhance the removal efficiency

Keywords： hydroxide     surplus     aeration     SMBR     Bioferric process    

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Development of combined coagulation-hydrolysis acidification-dynamic membrane bioreactor system for treatment

Xue Shen, Lei Lu, Baoyu Gao, Xing Xu, Qinyan Yue

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 1, doi: 10.1007/s11783-019-1093-8

Abstract:

• We created a combined system for treating oilfield polymer-flooding wastewater.

• The system was composed of coagulation, hydrolysis acidification and DMBR.

• Coagulant integrated with demulsifier dominated the removal of crude oil.

• The DMBR proceed efficiently without serious membrane fouling.

Keywords： Coagulation     Hydrolysis acidification     Dynamic membrane bioreactor     Polymer flooding    

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Performance of inverse fluidized bed bioreactor in treating starch wastewater

M. RAJASIMMAN, C. KARTHIKEYAN

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 3,   Pages 235-239 doi: 10.1007/s11705-009-0020-0

Abstract: Aerobic digestion of starch industry wastewater was carried out in an inverse fluidized bed bioreactor

Keywords： inverse fluidization     low-density particles     polypropylene     starch     biofilm    

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Energy reduction of a submerged membrane bioreactor using a polytetrafluoroethylene (PTFE) hollow-fiber

Taro Miyoshi, Thanh Phong Nguyen, Terumi Tsumuraya, Hiromu Tanaka, Toru Morita, Hiroki Itokawa, Toshikazu Hashimoto

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 3, doi: 10.1007/s11783-018-1018-y

Abstract: In this study, we modified a polytetrafluoroethylene (PTFE) hollow-fiber membrane element used for submerged membrane bioreactors (MBRs) to reduce the energy consumption during MBR processes. The high mechanical strength of the PTFE membrane made it possible to increase the effective length of the membrane fiber from 2 to 3 m. In addition, the packing density was increased by 20% by optimizing the membrane element configuration. These modifications improve the efficiency of membrane cleaning associated with aeration. The target of specific energy consumption was less than 0.4 kWh·m in this study. The continuous operation of a pilot MBR treating real municipal wastewater revealed that the MBR utilizing the modified membrane element can be stably operated under a specific air demand per membrane surface area (SAD ) of 0.13 m ·m ·hr when the daily-averaged membrane fluxes for the constant flow rate and flow rate fluctuating modes of operation were set to 0.6 and 0.5 m ·m ·d , respectively. The specific energy consumption under these operating conditions was estimated to be less than 0.37 kWh·m . These results strongly suggest that operating an MBR equipped with the modified membrane element with a specific energy consumption of less than 0.4 kWh·m is highly possible.

Keywords： Energy-saving     Membrane bioreactor     Polytetrafluoroethylene (PTFE) membrane     Hollow fiber     Power consumption    

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Engineering application of membrane bioreactor for wastewater treatment in China: Current state and future

Kang XIAO, Ying XU, Shuai LIANG, Ting LEI, Jianyu SUN, Xianghua WEN, Hongxun ZHANG, Chunsheng CHEN, Xia HUANG

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 6,   Pages 805-819 doi: 10.1007/s11783-014-0756-8

Abstract: China has been the forerunner of large-scale membrane bioreactor (MBR) application.

Keywords： membrane bioreactor (MBR)     engineering application     wastewater treatment     review     China    

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Effects of hydraulic retention time on net present value and performance in a membrane bioreactor treating

Dawei Yu, Jianxing Wang, Libin Zheng, Qianwen Sui, Hui Zhong, Meixue Cheng, Yuansong Wei

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 6, doi: 10.1007/s11783-020-1280-7

Abstract: Abstract • The membrane bioreactor cost decreased by 38.2% by decreasing HRT from 72 h to 36 h. • Capitaland operation costs contributed 62.1% and 37.9% to decreased costs. • The membrane bioreactor is 32.6%A cost sensitivity analysis was performed for an industrial membrane bioreactor to quantify the effectsField experimental data from the membrane bioreactor, both full-scale (500 m3/d) and pilot (1.0 m3/d)The results showed that the tank cost was estimated above membrane cost in the membrane bioreactor.

Keywords： Antibiotic production wastewater     Net present value     Membrane bioreactor     Hydraulic retention time     Pollutant    

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Simulation of long-term nutrient removal in a full-scale closed-loop bioreactor for sewage treatment:

Zheng LI,Rong QI,Wei AN,Takashi MINO,Tadashi SHOJI,Willy VERSTRAETE,Jian GU,Shengtao LI,Shiwei XU,Min YANG

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 3,   Pages 534-544 doi: 10.1007/s11783-014-0660-2

Abstract: In this study, the performance of nitrogen and phosphorus removal in a full-scale closed-loop bioreactor

Keywords： activated sludge model     Bayesian inference     biological nutrient removal     closed-loop bioreactor     oxidation    

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Two-phase Partitioning Bioreactor, Application of Cloud Point System in Bioconversion

Wang Zhilong

Strategic Study of CAE 2005, Volume 7, Issue 5,   Pages 73-78

Abstract:

The two-phase partitioning bioreactor is usually applied in many bioprocesses for enhancing the productivityThis article examines recent research on methods of the two-phase partitioning bioreactor.The practical potential of cloud point system as a novel two-phase partitioning bioreactor is illustrated

Keywords： two-phase partitioning     bioconversion     nonionic surfactant     cloud point system     bioreactor    

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Title Author Date Type Operation

Real time monitoring of bioreactor mAb IgG3 cell culture process dynamics via Fourier transform infraredspectroscopy: Implications for enabling cell culture process analytical technology?

Huiquan Wu, Erik Read, Maury White, Brittany Chavez, Kurt Brorson, Cyrus Agarabi, Mansoor Khan

Journal Article

Methanation and chemolitrophic nitrogen removal by an anaerobic membrane bioreactor coupled partial nitrification

Journal Article

Preliminary study of groundwater denitrification using a composite membrane bioreactor

Lihui ZHANG, Guomin CAO, Yulei FEI, Hong DING, Mei SHENG, Yongdi LIU

Journal Article

Enhanced atrazine removal using membrane bioreactor bioaugmented with genetically engineered microorganism

LIU Chun, HUANG Xia

Journal Article

Recent advances in membrane bioreactor technology for wastewater treatment in China

Xia HUANG, Kang XIAO, Yuexiao SHEN

Journal Article

Bisphenol A removal from synthetic municipal wastewater by a bioreactor coupled with either a forward

Hongtao ZHU, Wenna LI

Journal Article

wastewater treatment plants retrofitted from the conventional activated sludge process to the membrane bioreactor

Journal Article

Performance of bioferric-submerged membrane bioreactor for dyeing wastewater treatment

ZOU Haiyan, XI Danli

Journal Article

Development of combined coagulation-hydrolysis acidification-dynamic membrane bioreactor system for treatment

Xue Shen, Lei Lu, Baoyu Gao, Xing Xu, Qinyan Yue

Journal Article

Performance of inverse fluidized bed bioreactor in treating starch wastewater

M. RAJASIMMAN, C. KARTHIKEYAN

Journal Article

Energy reduction of a submerged membrane bioreactor using a polytetrafluoroethylene (PTFE) hollow-fiber

Taro Miyoshi, Thanh Phong Nguyen, Terumi Tsumuraya, Hiromu Tanaka, Toru Morita, Hiroki Itokawa, Toshikazu Hashimoto

Journal Article

Engineering application of membrane bioreactor for wastewater treatment in China: Current state and future

Kang XIAO, Ying XU, Shuai LIANG, Ting LEI, Jianyu SUN, Xianghua WEN, Hongxun ZHANG, Chunsheng CHEN, Xia HUANG

Journal Article

Effects of hydraulic retention time on net present value and performance in a membrane bioreactor treating

Dawei Yu, Jianxing Wang, Libin Zheng, Qianwen Sui, Hui Zhong, Meixue Cheng, Yuansong Wei

Journal Article

Simulation of long-term nutrient removal in a full-scale closed-loop bioreactor for sewage treatment:

Zheng LI,Rong QI,Wei AN,Takashi MINO,Tadashi SHOJI,Willy VERSTRAETE,Jian GU,Shengtao LI,Shiwei XU,Min YANG

Journal Article

Two-phase Partitioning Bioreactor, Application of Cloud Point System in Bioconversion

Wang Zhilong

Journal Article